Endocrine Abstracts

Background: In clinical practice, hirsutism is commonly seen among women of fertile age and defined as the presence of terminal hair with male distribution in women.Objective: The aim of the study was to assess the clinical, biochemical and etiologic features of hirsutism in women from the oriental region of Morocco.Materials and methods: 36 female patients presenting with hirsutism at Department of Endocrinology, Mohammed VI Hospi...

Introduction: Turner syndrome is a chromosomal abnormality that affects phenotypic females who have one intact X chromosome and complete or partial absence of the second sex chromosome. In this genetic disease, the karyotype ranges from complet 45, X to forms of mosaicism in which a normal cell line (46, XX or 46, XY) or a second (or third) abnormal cell line is found. Mosaic turner syndrome (MTS) has a heterogeneous clinical presentation as well as a varied presence of malfor...

Context: The genes implicated in premature ovarian failure play a role in crucial biologic processes such as DNA repair, meiosis, germ cell recruitment, steroidogenesis and mitochondrial function. Mitochondrial disorders are varied in their onset, inheritance pattern, and clinical presentation, but they often cause dysfunction in organs with high energy demands. Frequent features include hypertrophic cardiomyopathy, heart conduction defects, myopathy, sensorineural deafness, c...